Cefpodoxime Proxetil Tablets for Dogs (10 Pills)


Strength: 100-mg (10 Pills)

This item requires an active prescription from a vet visit within the last 12 months Details We'll collect your pet and vet information to verify this prescription before shipping..

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Cefpodoxime Proxetil is a prescription medication for dogs to treat bacterial infections of the skin including wounds and abscesses, as well as bladder and respiratory infections. Plus, since this medication comes in an oral tablet form, it can be easily disguised in your dog’s favorite food. Customers may receive this drug under the names Simplicef, Vantin.


Cefpodoxime Proxetil Tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs.

Possible Side Effects

Stop administering and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.

Drug & Food Interactions

Do not give medication at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.


As with other cephalosporins, cefpodoxime proxetil may occasionally induce a positive direct Coombs’ test.

NOTE: For Generic Medications, the picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color, and shape depending on the manufacturer. Customers may receive the same drug under the names Simplicef, Vantin.

Recommended Dosage

Give this medication by mouth according to a veterinarian's instructions as they will be able to determine the dose and frequency best suitable for your dog.

Storage Instructions

Store at controlled room temperatures between 68° - 77°F. Replace cap securely after each opening.


What is Cefpodoxime proxetil?

Cefpodoxime proxetil is an oral cephalosporin antibiotic used to treat bacterial infections of the skin, such as wounds and abscesses as well as bladder and respiratory infections in dogs.

What are the benefits of Cefpodoxime Proxetil Tablets?

  • Treats bacterial skin, bladder, and respiratory infections in dogs.
  • Simple oral once-daily dosing.
  • It comes in a film-coated tablet for easy administration.

How is this medication given?

Give this medication exactly as directed by your veterinarian. The usual dose of cefpodoxime proxetil in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days up to a maximum of 28 days.

How does this medication work?

It is a cephalosporin antibiotic that treats bacterial infections by suppressing the growth of micro-organisms such as bacteria, fungi, or protozoa.

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